Insulin resistance is a widespread health issue that affects millions of people worldwide. Despite its prevalence, many are unaware of how this condition directly contributes to weight gain and hinders weight loss efforts. Insulin resistance occurs when the body’s cells become less responsive to insulin, a hormone essential for regulating blood sugar levels. This leads to elevated blood sugar, which the body then stores as fat, making weight loss significantly more challenging.
So, how do we find out if insulin resistance is the reason you are fat? Well, we can ask experts on the field, such as Mike Diamonds.
Dr. Mike Diamond is a former medical doctor who is now an online fitness coach and YouTuber. He has got more than a million subscribers to his channel and usually uses himself in his body transformation as an example of how he can help people become their better selves. He is also the founder of a website called “Sculpt by Science.”
In this comprehensive guide, we will delve into what insulin resistance is, its causes, and most importantly, how you can overcome it through lifestyle changes.
Table of Contents
What is Insulin?
Insulin is a hormone produced by the pancreas that plays a critical role in transporting glucose (blood sugar) into cells for energy. It helps regulate blood sugar levels by signaling to cells in muscles, the liver, and fat tissues to absorb glucose from the bloodstream. When functioning correctly, insulin ensures that blood sugar levels remain within a healthy range, preventing hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).
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What is Insulin Resistance?
Insulin resistance is a condition where the cells in your body become less responsive to insulin. This means that even though your pancreas is producing insulin, the cells aren’t absorbing glucose from the bloodstream as efficiently as they should. As a result, glucose remains in the blood for longer periods, leading to elevated blood sugar levels.
“When insulin is functioning correctly, it helps transport glucose into the liver and muscle cells where the glucose is then used for energy or stored in fat cells for future use. Insulin resistance is a condition where the insulin fails to deliver the glucose into the cell. This means that the glucose is still in the blood,” explains Mike Diamonds.
This persistent high blood sugar forces the pancreas to produce more insulin in an attempt to manage the glucose levels. Over time, this overproduction can wear out the pancreas, reducing its ability to produce sufficient insulin, potentially leading to pre-diabetes or type 2 diabetes. Additionally, the excess glucose is often converted to fat, contributing to weight gain and making weight loss more difficult.

- Family History and Genetics: Genetics play a significant role in the likelihood of developing insulin resistance. If you have a family history of diabetes or insulin resistance, you are at a higher risk. “One of the biggest factors that determine and decide whether you’ll become insulin resistant or not is your genetics. If members of your family have had diabetes, then you’re more likely to do so too,” says Mike Diamonds.
- Obesity: Excess body fat, especially around the abdomen, is closely linked to insulin resistance. Obesity can cause inflammation and hormonal imbalances that disrupt insulin function. “Obesity can cause inflammation, hormonal fluctuations, and increase the amount of fatty acids, all of which have been shown to cause the development of insulin resistance,” Mike Diamonds notes.
- Sedentary Lifestyle: Lack of physical activity contributes to weight gain and can lead to insulin resistance. Regular exercise helps maintain healthy insulin levels by increasing glucose uptake in muscles. “Studies have shown that a sedentary lifestyle can rapidly lead to insulin resistance,” says Mike Diamonds.
- High Carb Diets: Diets high in refined sugars and processed carbohydrates can lead to spikes in blood sugar and insulin levels, promoting insulin resistance over time. “When I say a high carb diet may increase insulin resistance, I’m talking about high carb diets mostly made up of high sugar foods and very high in calories,” explains Mike Diamonds.
- Nicotine: Smoking and nicotine use are associated with increased inflammation and impaired insulin sensitivity. “Many of the chemicals in cigarettes cause inflammation, which affects how your cells respond to insulin,” notes Mike Diamonds.
- Insomnia and Poor Sleep: Lack of quality sleep can affect insulin sensitivity and glucose metabolism, leading to higher blood sugar levels. “Bad sleep can also affect your appetite and cause you to seek out high-calorie foods, leading to weight gain, another significant risk factor,” says Mike Diamonds.
Symptoms of Insulin Resistance
The symptoms of insulin resistance can be subtle and are often overlooked. Here are some common indicators:
- Large Waistline: Excess abdominal fat is a significant symptom of insulin resistance. “A large waistline is one of the biggest symptoms,” says Mike Diamonds.
- High Blood Pressure: Insulin resistance is often associated with high blood pressure.
- High Cholesterol Levels: Imbalances in blood lipid levels, including high cholesterol, can be a sign of insulin resistance.

“Many of these symptoms are impossible to spot on your own, but if you have a large waistline, go and see your doctor and get the following blood tests: blood glucose test, cholesterol test, and blood pressure tests,” advises Mike Diamonds.
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Is Insulin Resistance the Reason You Are Fat?
Insulin resistance is a significant factor that can contribute to weight gain and make it more challenging to lose weight, but it is not the sole reason people get fat. Insulin resistance occurs when the body’s cells become less responsive to insulin, leading to elevated blood sugar levels. When the cells do not absorb glucose effectively, the pancreas produces more insulin to manage the blood sugar levels. However, this excess glucose is often stored as fat, particularly around the abdominal area, contributing to weight gain.
Key Points on Insulin Resistance and Weight Gain
- Elevated Blood Sugar: Insulin resistance causes elevated blood sugar levels because the cells are not efficiently absorbing glucose. The body compensates by producing more insulin, but the prolonged high blood sugar levels can lead to fat storage.
“When insulin is functioning correctly, it helps transport glucose into the liver and muscle cells where the glucose is then used for energy or stored in fat cells for future use. Insulin resistance is a condition where the insulin fails to deliver the glucose into the cell. This means that the glucose is still in the blood.” – Mike Diamonds
- Fat Storage: When insulin is unable to efficiently transport glucose into the cells, the excess glucose is stored in fat cells. This process is particularly prominent in the liver and muscle cells, leading to an increase in body fat.
“Once the liver and the muscle cells are full, any additional glucose is sent to your fat cells for storage.” – Mike Diamonds
- Challenges in Weight Loss: Insulin resistance makes losing weight more difficult because the body tends to store excess blood sugar as fat. Even with efforts to reduce calorie intake and increase physical activity, the body’s impaired insulin response can hinder effective weight loss.
Other Contributing Factors

While insulin resistance is a major factor, it is not the only cause of weight gain. Other contributing factors include:
- Diet: High intake of refined sugars and processed carbohydrates can lead to spikes in blood sugar and insulin levels, promoting fat storage.
- Physical Activity: A sedentary lifestyle can lead to weight gain and contribute to insulin resistance.
- Genetics: Family history and genetic predisposition can influence one’s likelihood of developing insulin resistance and obesity.
- Sleep: Poor sleep quality and duration can affect metabolism and insulin sensitivity, leading to weight gain.
- Smoking: Nicotine use is associated with increased inflammation and impaired insulin sensitivity, contributing to weight gain.
How to Fix Insulin Resistance
- Increase Daily Activity Levels: Regular physical activity helps improve insulin sensitivity and reduces fat stores. Aim to incorporate activities such as walking, swimming, or strength training into your daily routine. Setting a goal of 8,000 steps per day is a good start.
- Improve Sleep Quality and Quantity: Establishing a regular sleep schedule and ensuring you get at least 8 hours of sleep per night can significantly improve insulin sensitivity. Avoiding caffeine in the late afternoon and reducing screen time before bed can enhance sleep quality.
- Dietary Changes: Focus on a balanced diet rich in protein, fiber, and healthy fats while reducing intake of refined sugars and processed foods. Increase your intake of vegetables, whole grains, and lean proteins to stabilize blood sugar levels.
- Reduce Overall Body Fat Levels: Creating a caloric deficit through a combination of diet and exercise is crucial for fat loss. This can be achieved by eating smaller portion sizes and engaging in regular physical activity.
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Insulin resistance is a serious condition that can significantly impact your health and weight. However, with the right lifestyle changes, it is possible to reverse insulin resistance and improve your overall health. Focus on increasing physical activity, improving sleep, making dietary changes, and reducing body fat. By taking these steps, you can enhance your insulin sensitivity and make your weight loss journey more effective. Remember, small, consistent changes can lead to significant health improvements over time.
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image sources
- Doctor and body fat: Lucas Guimarães Bueno on Pexels
- Bulking and cutting: Julia Larson / Pexels